HBOT Indications
HBOT creates an atmosphere conducive to healing aiding in the recovery from a variety of illnesses and conditions
By breathing almost pure oxygen in a pressurized room, increased oxygen is delivered to the patient’s bloodstream which can enhance the healing of numerous conditions.
We anticipate processing claims through most major insurance carriers and Medicare for the following indications (please note this is a partial list)
- Prophylactic pre- and post-treatment for those undergoing dental surgery of a radiated jaw, where the extractions site is anticipated to be within the XRT portal, and where HBOT Is delivered according to established (MARX) protocol, with 20 HBOT treatments prior to surgery and 10 HBOT treatments immediately after surgery.
- Idiopathic sudden deafness, acoustic trauma or noise-induced hearing loss, when HBOT is indicated within 3 months of onset
- Wound management/deep ulcers (note there are criteria for depth and management of the wound required to determine coverage)
- Compromised skin grafts and flaps, where hypoxia or decreased perfusion has compromised viability
- Radiation or chemotherapy-induced hemorrhagic cystitis
- Radiation necrosis (brain, muscle, bone and soft tissue), including radiation proctitis
- Chronic refractory osteomyelitis
Other Potential Indications (may not be covered by insurance)
- Traumatic brain injury (TBI)
- Chronic post-stroke state
- Augment the management of lyme disease
- Chronic pain-fibromyalgia, headaches, neuropathic pain
- Post traumatic stress disorder (ptsd)
- Cognitive impairment
- Attenuation of atherosclerosis
- GI conditions such as inflammatory bowel disease and radiation proctitis
- Sports injuries
- Urologic conditions such as interstitial cystitis
- Other indications as felt to be evidence-based may be considered
Learn more about our HBOT treatments
Resources
TBI-Traumatic Brain Injury
References
- Efrati S and Ben-Jacob, E Reflections on the neurotherapeutic effects of hyperbaric oxygen Expert Rev. Neurother. 14(3), 233-236 (2014)
- Boussi-Gross R, et al Hyperbaric Oxygen Therapy Can Improve Post Concussion Syndrome Years after Mild Traumatic Brain Injury-Randomized Prospective Trial PLOS ONE November 2013 Vol 8 Issue 11; 1-18 Read the article
- Harch PG, Andrews SR, Fogarty EF, LucarinimJ and Van Meter KW Case control study: hyperbaric oxygen treatment of mild traumatic brain injury persistent post-concussion syndrome and post-traumatic stress disorder Medical Gas Research vol 7; issue 3; Sept 2017; 1-93 Hyperbaric oxygen in traumatic brain injury. Neurol Res. 2007 Mar;29(2):162-72 Read the article
- Harch PG, Fogarty EF, Staab PK and Van Meter K Low pressure hyperbaric oxygen therapy and SPECT brain imaging in the treatment of blast-induced chronic traumatic brain injury (post-concussion syndrome) and post traumatic stress disorder: a case report Cases Journal 2009, 2:6538 Read the article
- Harch PG, Kridt C, Van Meter KW and Sutherland RJ Hyperbaric oxygen therapy improves spatial learning and memory in a rat model of chronic traumatic brain injury Brain Research 1174 (2007) 120-129 Read the article
- GOLDEN Z, GOLDEN CJ & NEUBAUER RA Improving neuropsychological function after chronic brain injury with hyperbaric oxygen Disability and Rehabilitation, November 2006; 28(22): 1379 – 1386 Read the article
- Neubauer RA, Neubauer V, Gerstenbrand F Late Treatment of Severe Brain Injury with Hyperbaric OxygenationJournal of American Physicians and Surgeons Volume 10 Number 2 Summer 2005 Read the article
- Zhang T, Yang QW, Wang SN, Wang JZ, Wang Q, Wang Y, Luo YJ. Hyperbaric oxygen therapy improves neurogenesis and brain blood supply in piriform cortex in rats with vascular dementia Brain Inj. 2010 Aug 17. Read the article
- Vila JF, Balcarce PE, Abiusi GR, Dominguez RO, Pisarello JB. Improvement in motor and cognitive impairment after hyperbaric oxygen therapy in a selected group of patients with cerebrovascular disease: a prospective single-blind controlled trial.Undersea Hyperb Med. 2005 Sep-Oct;32(5):341-9 Read the article
- Wright, James K (11/2009). “Case report: Treatment of mild traumatic brain injury with hyperbaric oxygen”. Undersea & hyperbaric medicine (1066-2936), 36 (6), 391. Read the article
- Al-Waili NS, Butler GJ, Beale J, Abdullah MS, Hamilton RW, Lee BY, Lucus P, Allen MW, Petrillo RL, Carrey Z, Finkelstein M. Hyperbaric oxygen in the treatment of patients with cerebral stroke, brain trauma, and neurologic disease. Ther. 2005 Nov-Dec; 22(6):659-78. Read the article
- Figuero XA and Wright JK Hyperbaric Oxygen: B-Level evidence in mild Traumatic Brain Injury Clinical Trials Neurology 2015; 70165 Read the article
- Eovaldi B; Zanetti C. Hyperbaric oxygen ameliorates worsening signs and symptoms of post-traumatic stress disorder. Neuropsychiatr Dis Treat. 2010 Dec 06; Vol. 6, pp. 785-9. PMID: 21212826; ISSN: 1178-2021. Read the article
- Harch PG, Andrews SR, Fogarty EF, LucarinimJ and Van Meter KW Case control study: hyperbaric oxygen treatment of mild traumatic brain injury persistent post-concussion syndrome and post-traumatic stress disorder Medical Gas Research vol 7; issue 3; Sept 2017; 1-93
- Harch PG, Fogarty EF, Staab PK and Van Meter K Low pressure hyperbaric oxygen therapy and SPECT brain imaging in the treatment of blast-induced chronic traumatic brain injury (post-concussion syndrome) and post-traumatic stress disorder: a case report Cases Journal 2009, 2:6538 Read the article
- GOLDEN Z, GOLDEN CJ & NEUBAUER RA Improving neuropsychological function after chronic brain injury with hyperbaric oxygen Disability and Rehabilitation, November 2006; 28(22): 1379 – 1386 Read the article
- Efrati, S Hyperbaric Oxygen Induces Late Neuroplasticity in Post Stroke Patients-Randomized, Prospective Trial POLS ONE January 2013 vol 6;Issue 1 ; 1-10 Read the article
- Holbach KH, Wassmann HW and Hoheluchter KL Reversibility of the chronic post-stroke state Stroke 1976;7;296-300 Read the article
- Ying-Sheng Lee et al Long Course Hyperbaric Oxygen Stimulates Neurogenesis and Attenuates Inflammation after Ischemic Stroke Mediators of Inflammation Vol 2013,Article ID 512978 Read the article
- Li Sun, Hugo H. Marti and Roland Veltkamp Hyperbaric Oxygen Reduces Tissue Hypoxia and Hypoxia-Inducible Factor-1α Expression in Focal Cerebral Ischemia Stroke. 2008;39:1000-1006; originally published online January 31, 2008 Read the article
- Cheng-Hsin Chen, Effects of Repetitive Hyperbaric Oxygen Treatment in Patients with Acute Cerebral Infarction: A Pilot Study The Scientific World Journal Volume 2012, Article ID 694703 1-5 Read the article
- Kidd PM Integrated Brain Restoration after Ischemic Stroke – Medical Management, Risk Factors, Nutrients, and other Interventions for Managing Inflammation and Enhancing Brain Plasticity Alternative Medicine Review Volume 14, Number 1 2009 Read the article
- Morton Walker, D.P.M.Reversal of Residual Stroke Symptoms Using Hyperbaric Oxygen Therapy Read the article
- Richard A. Neubauer, M.D. and Edgar End, M.D. HYPERBARIC OXYGENATION AS AN ADJUNCT THERAPY IN STROKES DUE TO THROMBOSIS A Review of 122 Patients STROKE 11(3): 297-300, 1980.
- Al-Waili NS, Butler GJ, Beale J, Abdullah MS, Hamilton RW, Lee BY, Lucus P, Allen MW, Petrillo RL, Carrey Z, Finkelstein M. Hyperbaric oxygen in the treatment of patients with cerebral stroke, brain trauma, and neurologic disease. Adv. Ther. 2005 Nov-Dec; 22(6):659-78. Read the article
- Hadanny A, et al Hyperbaric oxygen can induce neuroplasticity and improve cognitive functions of patients suffering from anoxic brain damage Restor Neurol Neurosci 2015; 33(4): 471-486 Read the article
- Yang, L, Hei MY, Dai JJ, Hu N and Xiang XY Effect of hyperbaric oxygenation on mitochondrial function of neuronal cells in the cortex of neonatal rats after hypoxic-ischemic brain damage Braz J Med Biol Res 2016; 49(5); e5187 Read the article
- Harch PG, et al. SPECT brain imaging and low pressure HBO in the diagnosis and treatment of chronic traumatic, ischemic, hypoxic and anoxic encephalopathies. Undersea and Hyperbaric Med. 1994 (Supp) 4/5 showed improvement in focal cortical & deep grey matter deficits. Read the article
- Dr Shor on HBOT and Lyme-Kaplan Clinic March 6, 2014 Watch the video
- Brooke Landau Lyme Disease Battle (ABC News Story)-July 25, 2010 Watch the video
- Huang CY et al Hyperbaric oxygen therapy as an effective adjunctive treatment for chronic Lyme disease J of the Chinese Medical Association; xx (2014) 1-3 Read the article
- Taylor RS, Simpson IN Review of treatment options for Lyme borreliosis. J Chemother. 2005 Sep;17 Suppl 2:3-16 Read the article
- Fife WP, Neubauer RA. Hyperbaric oxygenation for Lyme Vasculitis. 26th Annual Meeting of the European Underwater and Baromedical Society on Diving and Hyperbaric Medicine, Malta, September 14-17, 2000. Read the article
- Fife, William P; Freeman, DM (Jan 29, 1998). “Treatment of Lyme disease with hyperbaric oxygen therapy” Undersea and Hyperbaric Medical Society Annual Meeting Abstract.
- Whitehouse CA, Williams LR and Austin FE Identification of superoxide dismutase activity in Borrelia burgdorferie Immun. November 1997vol. 65 no. 11 4865-4868 Read the article
- Hadanny A, et al Hyperbaric oxygen can induce neuroplasticity and improve cognitive functions of patients suffering from anoxic brain damage Restor Neurol Neurosci 2015; 33(4): 471-486 Read the article
- Scholey AB, Moss MC, Neave N and Wsens K Cognitive Performance, Hyperoxia and Heart Rate Following Oxygen Adminstration in Healthy Young Adults Physiol Behav 1999 67(5): 783-9 Read the article
- Zhang T, Yang QW, Wang SN, Wang JZ, Wang Q, Wang Y, Luo YJ. Hyperbaric Oxygen Therapy Can Improve Post Concussion Syndrome Years after Mild Trauma-Brain Inj. 2010;24(11):1350-7. Read the article
- Efrati S and Ben-Jacob, E Reflections on the neurotherapeutic effects of hyperbaric oxygen Expert Rev. Neurother. 14(3), 233-236 (2014) Read the article
- Boussi-Gross R, et al umatic Brain Injury-Randomized Prospective Trial PLOS ONE November 2013 Vol 8 Issue 11; 1-18 Read the article
- Yang, L, Hei MY, Dai JJ, Hu N and Xiang XY Effect of hyperbaric oxygenation on mitochondrial function of neuronal cells in the cortex of neonatal rats after hypoxic-ischemic brain damage Braz J Med Biol Res 2016; 49(5); e5187 Read the article
- Al-Waili NS, Butler GJ, Beale J, Abdullah MS, Hamilton RW, Lee BY, Lucus P, Allen MW, Petrillo RL, Carrey Z, Finkelstein M. Hyperbaric oxygen in the treatment of patients with cerebral stroke, brain trauma, and neurologic disease. Adv. Ther. 2005 Nov-Dec; 22(6):659-78. Read the article
- Efrati, S et al Hyperbaric Oxygen Therapy Can Diminish Firbromyalgia Syndrome-Prospective Clinical Trial PLoS ONE 10(5): e0127012. doi:10.137/journal.pone.0127012 May 26, 2015 Read the article
- Yildiz S, Kiralp MZ, Akin A, Keskin I, Ay H, Dursun H, Cimsit M. A new treatment modality for fibromyalgia syndrome: hyperbaric oxygen therapy. J Int Med Res. 2004 May-Jun;32(3):263-7 Read the article
- Kiralp MZ, Yildiz S, Vural D, Keskin I, Ay H, Dursun H. Effectiveness of hyperbaric oxygen therapy in the treatment of complex regional pain syndrome. J Int Med Res. 2004 May-Jun;32(3):258-62. Read the article
- Colleen D. Thompson a, Megan L. Uhelski a, Judy R. Wilson b, Perry N. Fuchs Hyperbaric oxygen treatment decreases pain in two nerve injury models Neuroscience Research 66 (2010) 279–283
- Tuter NV, Danilov AB, Poliakova LV: The treatment of a complex regional pain syndrome. Zh Nevrol Psikhiatr Im S S Korsakova 1997; 97: 33 – 35. Read the article
- Sutherland AM, Clarke HA, Katz J and Katznelson R Hyperbaric Oxygen Therapy: A New Treatment for Chronic Pain Pain Practice, Vol 16 Issue 5, 2016; 620-628 Read the article
- Daruwalla J and Christophi C Hyperbaric Oxygen Therapy for Malignancy: A Review World J Surg (2006) 30: 2112-2131 Read the article
- Stepien K, Ostrowski RP and Matyia E Hyperbaric oxygen as an adjunctive therapy of malignancies, including brain tumours Med Oncol. 2016; 33(9): 101 Read the article
- Moen I, Stuhr LE Hyperbaric oxygen therapy and cancer–a review. Target Oncol 2012 Dec;7(4):233-42. doi: 10.1007/s11523-012-0233-x. Epub 2012 Oct 2. Read the article
- Pande S, Sengupta A, Srivastava A, Gude RP, Ingle A. Re-evaluate the effect of hyperbaric oxygen therapy in cancer – a preclinical therapeutic small animal model study PLoS One 2012;7(11):e48432. doi: 10.1371/journal.pone.0048432. Epub 2012 Nov 7. Read the article
- Peng ZR, Zhong WH, Liu J, Xiao PT. Effects of the combination of hyperbaric oxygen and 5-fluorouracil on proliferation and metastasis of human nasopharyngeal carcinoma CNE-2Z cells. Undersea Hyperb Med. 2010 May-Jun;37(3):141-50. Read the article
- Poff AM, Ari C, Seyfried TN, D’Agostino DP The ketogenic diet and hyperbaric oxygen therapy prolong survival in mice with systemic metastatic cancer. PLoS One 2013 Jun 5;8(6):e65522. doi: 10.1371/journal.pone.0065522. Print 2013. Read the article
- Kawasoe Y, Yokouchi M, Ueno Y, Iwaya H, Yoshida H, Komiya S. Hyperbaric oxygen as a chemotherapy adjuvant in the treatment of osteosarcoma. Oncol Rep. 2009 Nov;22(5):1045-50 Read the article
- Daruwalla J, Greish K, Nikfarjam M, Millar I, Malcontenti-Wilson C, Iyer AK, Christophi C. Evaluation of the effect of SMA-pirarubicin micelles on colorectal cancer liver metastases and of hyperbaric oxygen in CBA mice. J Drug Target. 2007 Aug-Sep;15(7-8):487-95. Read the article
- Haroon AT, Patel M, Al-Mehdi AB. Lung metastatic load limitation with hyperbaric oxygen Undersea Hyperb Med. 2007 Mar-Apr;34(2):83-90. Read the article
- Kalns J, Krock L, Piepmeier E Jr. The effect of hyperbaric oxygen on growth and chemosensitivity of metastatic prostate cancer. Anticancer Res. 1998 Jan-Feb;18(1A):363-7. Read the article
- Mukherjee A et al Intensive rehabilitation combined with HBO2 therapy in children with cerebral palsy: A controlled longitudinal study UHM 2014,Vol.41,No.2 77-86 Read the article
- Efrati S and Ben-Jacob E How and why hyperbaric oxygen therapy can bring new hope for children suffereing from cerebral palsy-An editorial perspective UHM 2014,Vol.41,No.2 71-276 Read the article
- Collet JP et al Hyperbaric oxygen for children with cerebral palsy: a randomised multicentre trial. HBO-CP Research Group. Lancet 2001 Feb 24;357(9256):582-6 Read the article
- A. Neubauer, MD 1st International Symposium on Cerebral Palsy and the Brain Injured Child, Boca Raton, FL, July, 1999 Read the article
- Montgomery D., Effects of Hyperbaric Oxygen Therapy on Children with Spastic Diplegic Cerebral Palsy: A Pilot Project, Journal of Undersea & Hyperbaric Medicine, Vol. 26: No. 4: Winter 1999: p 235 – 242.
- Harch P Hyperbaric Oxygen Therapy in Cerebral Palsy and Pediatric Neurology: A Scientific Perspective Magazine June 2004 Read the article
- Hosokawa S et al Hyperbaric Oxygen Therapy as Adjuvant Treatment for Idiopathic Sudden Sensorineural Hearing Loss after Failure of Systemic Steroids Audiol Neurotol 2017;22:9-14 Read the article
- Imsuwansri T et al Hyperbaric Oxygen Therapy for Sudden Sensorineural Hearing Loss after Failure from Oral and Intratympanic Corticosteroid Clin Exp Otorhinolaryngol 2012 Apr; 5(Suppl 1): S99-S102 Read the article
- Korpinar S et al Factors influencing the outcome of idiopathic sudden sensorineural hearing loss treated with hyperbaric oxygen therapy Eur Arch Otorhinolaryngol (2011) 268:41–47
- “HBOT should be considered for the cases especially with total or profound hearing loss” Read the article
- Fattori B et al Sudden hypoacusis treated with hyperbaric oxygen therapy: a controlled study. Ear Nose Throat J 2001 Sep;80(9):655-60.
- “Significantly more patients in the HOT group experienced a good or significant response. In both groups, patients with pantonal hypoacusis responded significantly better than did those with a milder condition. Based on our findings, coupled with the fact that oxygen therapy is well tolerated and produces no side effects, we conclude that HOT should be considered the preferred treatment for patients with sudden hypoacusis.” Read the article
- Topuz E, Yigit O, Cinar U, Seven H.Should hyperbaric oxygen be added to treatment in idiopathic sudden sensorineural hearing loss? Eur Arch Otorhinolaryngol. 2004 Aug;261(7):393-6. Epub 2003 Oct 29. “In our prospective randomized study, we aimed to investigate the therapeutic effects of HBO therapy in the 1st 2 weeks of the onset of ISSHL. Fifty-one hospitalized patients with confirmed ISSHL who had received therapy were grouped randomly into two groups. Twenty-one patients (group I) received steroids, plasma expander dextrans (rheomacrodex), diazepam, pentoxiphylline and salt restriction, and 30 patients (group II) received the same basic treatment with the addition of HBO therapy….In conclusion, the addition of HBO therapy to conventional treatment modalities significantly improves the outcome of ISSHL, especially at the frequencies of 250, 500, 1,000 and 4,000 Hz and in hearing loss of above 61 dB. Furthermore, HBO therapy was found to be more effective in patients younger than 50 years.” Read the article
- Fujimura T, Suzuki H, Shiomori T, Udaka T, Mori T Hyperbaric oxygen and steroid therapy for idiopathic sudden sensorineural hearing loss Eur Arch Otorhinolaryngol (2007) 264:861–866 “HBO therapy shows a significant additional effect in combination with steroid therapy for ISSNHL, particularly in patients with severe hearing loss.” Read the article
- Rossignol DA Hyperbaric oxygen treatment for inflammatory bowel disease: a systematic review and analysis Med Gas Res. 2012; 2: 6 Read the article
- Gulec B, Yasar M, Yildiz S, Oter S, Akay C, Deveci S, Sen D. Effect of hyperbaric oxygen on experimental acute distal colitis. Physiol Res. 2004;53(5):493-9. Read the article
- Atug O, Hamzaoglu H, Tahan V, Alican I, Kurtkaya O, Elbuken E, Ozdogan O, Tozun N. Hyperbaric oxygen therapy is as effective as dexamethasone in the treatment of TNBS-E-induced experimental colitis. Dig Dis Sci. 2008 Feb;53(2):481-5 Read the article
- Buchman AL, Fife C, Torres C, Smith L, Aristizibal J. Hyperbaric oxygen therapy for severe ulcerative colitis. J Clin Gastroenterol. 2001 Oct; 33(4):337-9. Read the article
- Gorgulu S, Yagci G, Kaymakcioglu N, Ozkara M, Kurt B, Ozcan A, Kaya O, Sadir S, Tufan T. Hyperbaric oxygen enhances the efficiency of 5-aminosalicylic acid in acetic acid-induced colitis in rats. Dig Dis Sci. 2006 Mar; 51(3):480-7. Read the article
- Guven A, Gundogdu G, Uysal B, Cermik H, Kul M, Demirbag S, Ozturk H, Oter S. Hyperbaric oxygen therapy reduces the severity of necrotizing enterocolitis in a neonatal rat model. J Pediatr Surg. 2009 Mar; 44(3):534-40. Read the article
- Demirtürk L, Ozel M, Yazgan Y, Buchman AL. Therapeutic efficacy of hyperbaric oxygenation in ulcerative colitis refractory to medical treatment. J Clin Gastroenterol. 2002 Sep;35(3):286-7/ Read the article
- Gurbuz AK, Elbüken E, Yazgan Y, Yildiz S. A different therapeutic approach in severe ulcerative hyperbaric oxygen treatment. Rom J Gastroenterol. 2003 Jun;12(2):170-1. Read the article
- Karkŭmov M, Nikolov N, Georgiev L, Mitreva D, Uzunova A. Hyperbaric oxygenation as a part of the treatment of chronic ulcerohemorrhagic colitis. Vutr Boles. 1991;30(2):78-80. Read the article
- Nandi J, Saud B, Zinkievich JM, Yang ZJ, Levine RA. TNF-alpha modulates iNOS expression in an experimental rat model of indomethacin-induced jejunoileitis. Mol Cell Biochem. 2010 Mar; 336(1-2):17-24. Read the article
- Rachmilewitz D, Karmeli F, Okon E, Rubenstein I, Better OS. Hyperbaric oxygen: a novel modality to ameliorate experimental colitis. Gut. 1998 Oct; 43(4):512-8. Read the article
- Tanaka T, Kawashima H, Makino T, Kamikawa S, Kato N, Nakatani T. Hyperbaric oxygen therapy for interstitial cystitis resistant to conventional treatments. Int J Urol. 2007 Jun; 14(6):563-5. Read the article
- Tanaka T et al Hyperbaric oxygen therapy for painful bladder syndrome/interstitial cystitis resistant to conventional treatments: long-term results of a case series in Japan BMC Urology/2011 11:11 Read the article
- Villar DG et al Hyperbaric oxygen treatment in urology Jul 2011 Read the article
- Van Ophoven A, Rossbach G, Pajonk F, Hertle L. Safety and efficacy of hyperbaric oxygen therapy for the treatment of interstitial cystitis: a randomized, sham controlled, double-blind trial. J Urol. 2006 Oct; 176(4 Pt 1):1442-6. Read the article
- Hyperbaric oxygenation in combined treatment of interstitial cystitis. Urologiia. 2010 Jan-Feb;( 1):22-4. Read the article
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